With the growing demand for injectable treatments that improve skin quality and restore youthful volume, patients often ask: what is the difference between Profhilo and HArmonyCa? Both treatments work beneath the skin’s surface, but their purpose, formulation, and results are distinct.
Here’s a clear, clinic-led guide to help you understand how they compare.
What Is Profhilo?
Profhilo is not a dermal filler in the traditional sense. It contains pure hyaluronic acid (HA) and is designed to improve skin texture, hydration, and elasticity. Instead of adding volume or structure, Profhilo spreads across the skin like a ‘liquid moisturiser’ to stimulate collagen and elastin naturally.
It’s typically administered in five key points on each side of the face and is best suited to clients experiencing dullness, fine lines, or early signs of skin laxity. The result is a subtle, healthy glow and improved firmness, without altering facial contours.
What Is HArmonyCa?
HArmonyCa is a hybrid injectable that combines hyaluronic acid with calcium hydroxyapatite (CaHA). While HA hydrates and supports the skin, CaHA adds structure and stimulates long-term collagen production. It’s a dual-acting product that provides both lift and regenerative effects.
Unlike Profhilo, HArmonyCa is used to contour and firm areas of volume loss, such as the cheeks, jawline, and lower face. The calcium component also promotes neocollagenesis, meaning results can improve over time.
So, What Is the Difference Between Profhilo and HArmonyCa?
In short:
- Profhilo is ideal for skin hydration, elasticity, and glow, with no added volume.
- HArmonyCa delivers a subtle lifting effect while also improving skin quality.
Clients who want brighter, healthier-looking skin with no change in shape often choose Profhilo. Those seeking more structure or support in the lower face may be better suited to HArmonyCa.
Both are popular options in our Canon Street clinic, and in many cases, they can be used as part of a layered treatment plan.
Which One Should You Choose?
The best choice depends on your skin’s needs and your desired results. During consultation, our practitioners assess the quality of your skin, areas of concern, and how your face is ageing over time.
Some clients start with Profhilo in their early 30s for prevention, then transition to structural treatments like HArmonyCa in their 40s or 50s. Others may combine both, using Profhilo for hydration and HArmonyCa for lift.
Both are CE-marked, safe, and clinically tested for facial rejuvenation when used by trained professionals.
To find out which treatment is right for you, book a consultation with our expert team. We’ll help you understand the difference between Profhilo and HArmonyCa — and create a personalised plan for radiant, lifted skin.